Luliconaz Cream is used in the treatment of Fungal skin infections Directions for Use of Luliconaz Xl Cream 75gm Directions for Use of Luliconaz Xl Cream 75gm Luliconaz Cream is an antifungal medicine. It works by eradicating the fungi that are responsible for these diseases. Luliconaz Cream should be used according to your doctor's instructions for dosage and duration. Do not take it more frequently or in larger doses than suggested; this will not help you get better faster and may even worsen the adverse effects. After 2 to 4 weeks of usage, most skin infections will improve.