Lorapace HS 50mg/12.5mg Tablet is used to control high blood pressure in different ways. Lorapace HS 50mg/12.5mg Tablet is a combination of two medicines namely Losartan and Hydrochlorothiazide. It is generally used when one medicine alone is not controlling your blood pressure effectively. Losartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Hydrochlorothiazide is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.